pco.edge 4.2 bi USB sCMOS Camera
The pco.edge 4.2 bi sCMOS camera features back-illuminated sensor technology with a quantum efficiency of up to 95 %. This compact sCMOS camera achieves the highest image quality with a resolution of 2048 x 2048 pixels and a pixel size of 6.5 μm. Its adjustable cooling system offers flexibility in the use of either air or water to cool the sensor down to -25 °C and reduce dark current to 0.2 e-/pixel/s for maximum imaging performance. The pco.edge 4.2 bi camera comes with an input window available for either UV or VIS wavelength ranges to best suit your application.
The pco.edge 4.2 bi scientific camera provides excellent quantum efficiency combined with a high frame rate at 4.2 Megapixel resolution. This camera features a powerful USB 3.1 interface to continuously stream image data with full 16-bit dynamic range. Furthermore, the pco.edge 4.2 bi sCMOS camera includes sealed electronics to prevent dirt or dust from entering the camera.
| Interface | USB 3.1 Gen 1 |
| Sensor technology | back-illuminated sCMOS |
| Color type | monochrome |
| Resolution | 2048 x 2048 pixels |
| Sensor diagonal | 18.8 mm |
| Pixel size | 6.5 x 6.5 μm |
| Maximum frame rate @ full resolution | 40 fps |
| Maximum pixel rate | 184 MPixel/s |
| Peak QE | 95 % @ 580 nm |
| Typical read noise1 | 1.0 e- |
| Dark current @ sensor temperature | < 0.2 @ -25 °C (e-/pixel/s) |
| Maximum dynamic range | 26,667 : 1 |
| Shutter type | Rolling Shutter, Global Reset |
| Sensor cooling2 | air & water |
| Additional options | lightsheet scanning mode3, low light mode |
| Dimensions (H x W x L) | 85 x 80 x 109 mm |
- Brightfield microscopy microscopy
- Fluorescence microscopy
- Digital pathology
- Single molecule localization microscopy
- Lightsheet fluorescence microscopy (LSFM)
- Calcium imaging
- FRET
- FRAP
- Structured illumination microscopy (SIM)
- Highspeed bright field ratio imaging
- High throughput screening
- High content screening
- Biochip reading
- TIRF microscopy
- Spinning disk confocal microscopy
- 3D metrology
- Ophthalmology
- Photovoltaic inspection
- Industrial quality inspection
- Lucky astronomy
- Bio luminescence
- Chemo luminescence


| Interface | USB 3.1 Gen 1 |
| Sensor technology | back-illuminated sCMOS |
| Color type | monochrome |
| Resolution | 2048 x 2048 pixels |
| Sensor diagonal | 18.8 mm |
| Pixel size | 6.5 x 6.5 μm |
| Maximum frame rate @ full resolution | 40 fps |
| Maximum pixel rate | 184 MPixel/s |
| Peak QE | 95 % @ 580 nm |
| Typical read noise1 | 1.0 e- |
| Dark current @ sensor temperature | < 0.2 @ -25 °C (e-/pixel/s) |
| Maximum dynamic range | 26,667 : 1 |
| Shutter type | Rolling Shutter, Global Reset |
| Sensor cooling2 | air & water |
| Additional options | lightsheet scanning mode3, low light mode |
| Dimensions (H x W x L) | 85 x 80 x 109 mm |
- Brightfield microscopy microscopy
- Fluorescence microscopy
- Digital pathology
- Single molecule localization microscopy
- Lightsheet fluorescence microscopy (LSFM)
- Calcium imaging
- FRET
- FRAP
- Structured illumination microscopy (SIM)
- Highspeed bright field ratio imaging
- High throughput screening
- High content screening
- Biochip reading
- TIRF microscopy
- Spinning disk confocal microscopy
- 3D metrology
- Ophthalmology
- Photovoltaic inspection
- Industrial quality inspection
- Lucky astronomy
- Bio luminescence
- Chemo luminescence


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